Rockland/Anti-Human MIP-3a (MOUSE) Biotin Conjugated Antibody/209-306-B51/100 µg

来自 : 发布时间：2025-01-29

Anti-Human MIP-3a (MOUSE) Biotin Conjugated Antibody Properties Description Anti-Human MIP-3a (MOUSE) Biotin Conjugated Monoclonal Antibody - 209-306-B51 Host Mouse Target Species Human Known Cross Reactivity human Clonality Monoclonal 3N2D9 Application Western Blot : 0.5µg/mL Other Dilution: User Optimized Physical State Lyophilized Shipping Condition Ambient Format IgG Label Biotin FP Value 10-20 moles Biotin per mole of IgG Concentration 1.0 mg/mL by UV absorbance at 280 nm Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 Reconstitution Volume 100 µL Reconstitution Buffer Restore with deionized water (or equivalent) Preservative 0.01% (w/v) Sodium Azide Stabilizer 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free GeneName CCL20 Relevant Links UniProtKB - P78556GeneID - 6364NCBI - 4759076

Anti-Human MIP-3a (MOUSE) Biotin Conjugated Antibody Description

Background MIP-3a (also known as C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1) is a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. MIP-3a inhibits proliferation of myeloid progenitors in colony formation assays and may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. MIP-3a also possesses antibacterial activity against E.coli and S.aureus. MIP-3a is a secreted protein that is expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of expression are also seen in thymus, prostate, testis, small intestine and colon. C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes. Synonyms mouse anti-MIP-3 alpha Antibody biotin Conjugated, mouse anti-MIP-3a biotin Conjugated Antibody, MIP-3a , CCL20, C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1 Immunogen Anti-MIP-3a (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human MIP-3a produced in E.coli followed by hybridoma development. Immunogen Type Recombinant Protein Storage Condition Store vial at 4° C prior to restoration.   Restore with 0.1 mL of deionized water (or equivalent). For extended storage aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing.  Centrifuge product if not completely clear after standing at room temperature.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use. Application Note This purified antibody has been tested for use in Western Blot. Specific conditions for reactivity should be optimized by the end user. Purity/Specifity This product was purified from mouse ascites by Protein G chromatography followed by extensive dialysis against the buffer stated above. This antibody is specific for human MIP-3a protein. A BLAST analysis was used to suggest cross-reactivity with MIP-3a from human sources based on 100% homology with the immunizing sequence. Cross-reactivity with MIP-3a from other sources has not been determined. Disclaimer Note-General This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.